highsugar diet no problem for genetic mutants
Last Updated : GMT 06:49:16
Arab Today, arab today
Arab Today, arab today
Last Updated : GMT 06:49:16
Arab Today, arab today

High-sugar diet no problem for genetic mutants

Arab Today, arab today

Arab Today, arab today High-sugar diet no problem for genetic mutants

Cookies, and cake fill suger
Tehran - FNA

 Imagine being able to take a pill that lets you eat all of the ice cream, cookies, and cakes that you wanted - without gaining any weight.
New research from USC suggests that dream may not be impossible. A team of scientists led by Sean Curran of the USC Davis School of Gerontology and the Keck School of Medicine of USC found a new way to suppress the obesity that accompanies a high-sugar diet, pinning it down to a key gene that pharmaceutical companies have already developed drugs to target.
So far, Curran's work has been solely on the worm Caenorhabditis elegans and human cells in a petri dish -- but the genetic pathway he studied is found in almost all animals from yeast to humans. Next, he plans to test his findings in mice.
Curran's research is outlined in a study that will be published on Oct. 6 by Nature Communications.
Building on previous work with C. elegans, Curran and his colleagues found that certain genetic mutants -- those with a hyperactive SKN-1 gene -- could be fed incredibly high-sugar diets without gaining any weight, while regular C. elegans ballooned on the same diet.
"The high-sugar diet that the bacteria ate was the equivalent of a human eating the Western diet," Curran said, referring to the diet favored by the Western world, characterized by high-fat and high-sugar foods, like burgers, fries and soda.
The SKN-1 gene also exists in humans, where it is called Nrf2, suggesting that the findings might translate, he said. The Nrf2 protein, a "transcription factor" that binds to a specific sequence of DNA to control the ability of cells to detox or repair damage when exposed to chemically reactive oxygen (a common threat to cells' well being), has been well studied in mammals.
Pharmaceutical companies have already worked to develop small-molecule drugs that target Nrf2, in hopes that it will produce more anti-oxidants and slow aging.
Though the promise of a pill to help control your body's response to food is enticing, it is not without risk, Curran said. Increased Nrf2 function has been linked to aggressive cancers.
"Perhaps it is a matter of timing and location," Curran said. "If we can acutely activate Nrf2 in specific tissues when needed then maybe we can take advantage of its potential benefits."

 

arabstoday
arabstoday

GMT 19:03 2017 Saturday ,25 March

Five heart healthy habits

GMT 12:59 2017 Monday ,20 March

5 Tips to keep your eyes healthy

GMT 12:18 2017 Monday ,13 March

Top three yoga poses to improve your memory

GMT 14:45 2017 Wednesday ,22 February

You can enhance your brain

GMT 11:35 2017 Thursday ,16 February

Time-saving tips for you to have a little break
Arab Today, arab today

Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

highsugar diet no problem for genetic mutants highsugar diet no problem for genetic mutants

 



Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

highsugar diet no problem for genetic mutants highsugar diet no problem for genetic mutants

 



GMT 15:36 2017 Monday ,09 January

Major EU-GCC meeting in Riyadh today

GMT 17:19 2016 Thursday ,22 December

KFMC surgeons remove 28 kg tumor from woman’s uterus

GMT 17:33 2017 Wednesday ,16 August

Damac reports decline in property development sales

GMT 09:16 2018 Monday ,01 January

Seoul leaning towards military measures

GMT 01:05 2017 Wednesday ,20 December

No guarantees on French-German initiative on Ukraine

GMT 21:00 2017 Sunday ,17 September

Saif bin Zayed approves adoption of 'Emirati Reader'

GMT 02:10 2017 Thursday ,05 January

Bahrain Stock Index Drops 3.47 Points

GMT 02:05 2017 Thursday ,28 September

July24th-August23rd

GMT 04:17 2017 Saturday ,11 November

Laulala out to prove All Blacks worth against France

GMT 02:42 2017 Friday ,14 July

NATO Tripoli strike kills civilians

GMT 05:47 2017 Wednesday ,18 January

Mohamed bin Zayed attends opening of ADSW 2017
Arab Today, arab today
 
 Arab Today Facebook,arab today facebook  Arab Today Twitter,arab today twitter Arab Today Rss,arab today rss  Arab Today Youtube,arab today youtube  Arab Today Youtube,arab today youtube

Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2021 ©

Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2021 ©

arabstoday arabstoday arabstoday arabstoday
arabstoday arabstoday arabstoday
arabstoday
بناية النخيل - رأس النبع _ خلف السفارة الفرنسية _بيروت - لبنان
arabstoday, Arabstoday, Arabstoday