2 generic drugs reduce breast cancer deaths
Last Updated : GMT 06:49:16
Arab Today, arab today
Arab Today, arab today
Last Updated : GMT 06:49:16
Arab Today, arab today

Help cancel out undesirable side-effects

2 generic drugs reduce breast cancer deaths

Arab Today, arab today

Arab Today, arab today 2 generic drugs reduce breast cancer deaths

2 inexpensive classes of drugs available in generic form
Paris - Arab Today

Two inexpensive classes of drugs available in generic form each reduce the recurrence of breast cancer in post-menopausal women as well as death rates from the disease, a pair of studies reported.

Taking the medications together may further boost anti-cancer benefits and help cancel out undesirable side-effects of one of the drugs, according to the research published in medical journal The Lancet.

The first "meta-study" pulling together data from nine trials covering 30,000 post-menopausal women found endocrine treatments based on a class of drugs called aromatase inhibitors yield higher survival rates after five years compared to standard endocrine therapy with tamoxifen.

The likelihood of cancer recurring was cut by about a third and the risk of dying by about 15 percent in the decade after treatment started. Compared to no treatment at all, the danger of dying from breast cancer fell by 40 percent, the study found.

Most women have already passed through menopause when breast cancer strikes. Even after surgery has removed all detectable traces, tiny amounts of the body's own hormones can cause cancer cells to grow.

Endocrine therapies are designed to impede these hormones from stimulating the disease, and so help protect against relapse.

"But aromatase inhibitor treatment is not free of side-effects and it's important to ensure that women" who suffer them are "supported", said the study's lead author, Mitch Dowsett of The Institute of Cancer Research in London.

The second meta-study, which scanned the results of 26 trials involving another 20,000 women, showed that another class of drugs called bisphosphonates ?- usually taken to treat osteoporosis, a bone-weakening condition that becomes more common with age ?- also significantly boosted survival when taken for at least two years.

When breast cancer spreads, bone is its favoured destination. Tumour cells released from the primary breast cancer can remain dormant in bones for years before moving to other parts of the body.

Bisphosphonates make the bones a less hospitable environment for the cancer cells and so reduce the risk of cancer recurring. The beneficial effect were found to be far more pronounced in post-menopausal women, regardless of the treatment duration, the size of the tumour or whether the cancer had spread to lymph nodes.

The therapy did not, however, reduce the risk of new cancers developing in the opposite breast.

"These simple, well-tolerated treatments should now be considered for routine use" in women with natural or medically induced menopause, lead author Robert Coleman from the University of Sheffield said in a statement.

Some two-thirds of all women with breast cancer are post-menopausal with hormone-sensitive tumours, so could potentially benefit from both drugs, the researchers conclude.

"The drugs are complementary," noted Oxford University's Richard Gray, lead statistician for the studies. "The main side effect of aromatase inhibitors is an increase in bone loss and fractures, while bisphosphonates reduce bone loss."
Source: AFP

arabstoday
arabstoday

Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

2 generic drugs reduce breast cancer deaths 2 generic drugs reduce breast cancer deaths

 



Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

2 generic drugs reduce breast cancer deaths 2 generic drugs reduce breast cancer deaths

 



GMT 11:36 2016 Wednesday ,28 December

UAE Banks Needs Unified Approach To Common Problems

GMT 09:00 2017 Wednesday ,12 April

Colombia forces struggle to root out coca

GMT 21:42 2017 Monday ,06 February

Syria anti-Daesh forces say US sent them armored cars

GMT 18:35 2017 Saturday ,11 November

750,000 march for separatists' release in Barcelona

GMT 21:18 2016 Thursday ,22 September

Nawaz, Rouhani discuss bilateral ties, regional situation

GMT 18:31 2017 Friday ,01 September

Vietnam state oil magnate arrested in major fraud case

GMT 14:18 2017 Thursday ,09 March

CITC governor visits STC booth in Spain exhibition

GMT 04:30 2017 Friday ,10 November

Uber IPO 'target' is 2019

GMT 19:40 2017 Tuesday ,29 August

Mona used stones to decorate ornaments

GMT 13:02 2017 Wednesday ,08 March

Crash test dummies sacrifice lives for car safety

GMT 08:41 2017 Tuesday ,28 November

Beautiful Plants for Amazing Indoor Decoration

GMT 05:01 2018 Monday ,24 September

Bahrain weather forecast
Arab Today, arab today
 
 Arab Today Facebook,arab today facebook  Arab Today Twitter,arab today twitter Arab Today Rss,arab today rss  Arab Today Youtube,arab today youtube  Arab Today Youtube,arab today youtube

Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2021 ©

Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2021 ©

arabstoday arabstoday arabstoday arabstoday
arabstoday arabstoday arabstoday
arabstoday
بناية النخيل - رأس النبع _ خلف السفارة الفرنسية _بيروت - لبنان
arabstoday, Arabstoday, Arabstoday