experts support to offer unproven interventions to face ebola virus
Last Updated : GMT 06:49:16
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Last Updated : GMT 06:49:16
Arab Today, arab today

Experts support to offer unproven interventions to face Ebola virus

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Arab Today, arab today Experts support to offer unproven interventions to face Ebola virus

Ebola outbreak
Geveva - KUNA

The World Health Organization said on Tuesday that a panel of its experts reached consensus that it is ethical to offer unproven interventions with as yet unknown efficacy and adverse effects, as potential treatment or prevention to face Ebola virus.
"Ethical criteria must guide the provision of such interventions. These include transparency about all aspects of care, informed consent, freedom of choice, confidentiality, respect for the person, preservation of dignity and involvement of the community," said the WHO in a press release.
In order to understand the safety and efficacy of these interventions, the WHO group of experts advised that, if and when they are used to treat patients, there is a moral obligation to collect and share all data generated, including from treatments provided for 'compassionate use' (access to an unapproved drug outside of a clinical trial).
The group explored how the use of these interventions can be evaluated scientifically to ensure timely and accurate information about the safety and efficacy of these investigational interventions.
There was unanimous agreement that there is a moral duty to also evaluate these interventions (for treatment or prevention) in the best possible clinical trials under the circumstances in order to definitively prove their safety and efficacy or provide evidence to stop their utilization. Ongoing evaluation should guide future interventions.
In addition to this advice, the panel identified areas that need more detailed analysis and discussion, such as: ethical ways to gather data while striving to provide optimal care under the prevailing circumstances, ethical criteria to prioritize the use of unregistered experimental therapies and vaccines; ethical criteria for achieving fair distribution in communities and among countries, in the face of a growing number of possible new interventions, none of which is likely to meet demand in the short term.
West Africa is experiencing the largest, most severe and most complex outbreak of Ebola virus disease in history.
Ebola outbreaks can be contained using available interventions like early detection and isolation, contact tracing and monitoring, and adherence to rigorous procedures of infection control. However, a specific treatment or vaccine would be a potent asset to counter the virus.
Over the past decade, research efforts have been invested into developing drugs and vaccines for Ebola virus disease. Some of these have shown promising results in the laboratory, but they have not yet been evaluated for safety and efficacy in human beings.
The large number of people affected by the 2014 west Africa outbreak, and the high case-fatality rate, have prompted calls to use investigational medical interventions to try to save the lives of patients and to curb the epidemic.
Therefore, on 11 August 2014, WHO convened a consultation to consider and assess the ethical implications for clinical decision-making of the potential use of unregistered interventions.

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experts support to offer unproven interventions to face ebola virus experts support to offer unproven interventions to face ebola virus

 



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experts support to offer unproven interventions to face ebola virus experts support to offer unproven interventions to face ebola virus

 



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