Adults who were physically abused during childhood are more likely than their non-abused peers to have suicidal thoughts, new research shows. According to a new study, published online in the journal Suicide and Life-Threatening Behavior, approximately one-third of adults who were physically abused in childhood have seriously considered taking their own life—a rate that is five times higher than adults who were not physically abused in childhood. The findings suggest that children exposed to physical abuse may be at greater risk for suicidal behaviors in adulthood. Investigators examined gender specific differences among a sample of 6,642 adults, of whom 7.7 percent reported that they had been physically abused before the age of 18. A strong association between childhood physical abuse and subsequent suicidal behaviors remained even after taking into account other known risk factors, such as adverse childhood conditions, health behaviors, and psycho-social stressors. “This research provides important new knowledge about the enduring effects of abuse in childhood,” says lead author Esme Fuller-Thomson, professor of social work at the University of Toronto. “The findings have important clinical implications for healthcare providers, suggesting the need to screen for suicidal ideation among adults who have experienced childhood physical abuse and highlighting the importance of providing preventive treatment to childhood abuse survivors.” The findings open up further areas of research. Previous studies have theorized that habituation to high levels of pain and fear through childhood abuse may contribute to adults’ ability to inflict injury or harm on themselves. Recent research suggests suicide may have developmental origins relating to abuse—that physical or sexual abuse may lead to changes in the stress response in the brain which increase the risk of suicidal thoughts and behavior. Co-author Tobi Baker, a former graduate student at the University of Toronto, notes that “one important avenue for future research is to investigate the bio-psycho-social mechanisms through which childhood physical abuse may translate into suicidal behaviors.”