A feisty encounter is on the cards when the two outfits take to the Olimpico on Saturday, as the race for a top-three finish begins to hot up with the end of the season approaching.A surprise 3-1 reverse to Parma last weekend saw Lazio suffer a third defeat in four Serie A matches, but despite their recent poor form, they still lead the way in race for the last Champions League spot.However, Edy Reja\'s job isn\'t made any easier with the news that first-teamers Cristian Brocchi, Andre Dias, Miroslav Klose, Marius Stankevicius, Matuzalem, Stefan Radu and Senad Lulic will all miss out on the game against Napoli.As a result, a number of changes are on the horizon for the Romans as Mobido Diakite, Lionel Scaloni, Hernanes and Lorik Cana are likely to deputise for the absentees.For Napoli, coach Walter Mazzarri will be without injured trio Andrea Dossena, Marco Donadel and Christian Maggio, while Juan Zuniga and Walter Gargano are suspended. As a result, the 50-year-old is being tipped to switch to a 4-3-1-2 formation from his tried-and-trusted 3-5-2.Miguel Britos, Blerim Dzemaili and Goran Pandev are the players set to be flung into contention, with Hamsik dropping into midfield from his usual attacking role behind the strikers.