US Stocks closed lower on Thursday led by declines in health-care companies.

    The Dow Jones industrial average fell 33.07 points, or 0.2 percent, to 18,448.41. The S&P 500 gave up 2.97 points, or 0.1 percent, to 2,172.47. 

    The Nasdaq composite edged down 5.49 points, or 0.1 percent, to 5,212.20